Importance Of Protein During Weight Loss

Not all proteins are the same when it comes to weight loss.

Whey is well-suited to support muscle health during weight loss.

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Whey protein isolate is a complete, high-quality milk protein that has been ultra-filtered to remove the majority of the naturally occurring fats and sugar (lactose) found in milk. Gram for gram, it is one of the purest forms of protein on the planet and is the cornerstone ingredient from which ISOPURE® derives its name. High-quality protein sources, such as whey protein, naturally contain all nine of the essential amino acids (EAAs) in sufficient quantities. Whey naturally contains more leucine per gram of protein than other forms of proteins, which is a key EAA in stimulating muscle protein synthesis. 

Due to its essential amino acid content, especially leucine, whey has been shown to be more effective at stimulating muscle protein synthesis (fractional synthetic rate – FSR) than other proteins, like soy protein. A study by Hector et al in 2015 demonstrates that whey was more effective than soy or carbohydrate at stimulating muscle protein synthesis in overweight and obese adults, and this increase is preserved even during a 14 day energy-restricted diet.* 

Less is more – whey protein isolate (WPI) is more concentrated in protein compared to other sources, making it a very calorie efficient way of supplementing protein.

 

Protein Food Calories/20 g of Protein
ISOPURE® WPI Powder (Unflavored) 80
OPTIMUM NUTRITION® Casein Powder (Vanilla) 100
Chicken breast, meat only 106
PREMIER PROTEIN® (Vanilla) 107
Lean beef tenderloin 121
Fat-free cow’s milk 198
Unsweetened soy milk 214
Salmon 215
Whole large egg 246
Canned chickpeas 377
BOOST® (Vanilla) 480
ENSURE® Original (Vanilla) 488
Cooked quiona 545
Whey Protein Isolate is ultra-filtered to remove excess fat, carbohydrates, and sugar
Calories Protein Fat Sugar (lactose)
20g whey protein isolate 90 20g 0g 0g
1 baked chicken breast 70 15g 1g 0g
1 large boiled egg 80 6g 5g 1g
1 oz unsalted almonds 170 6g 15g 1g
1 cup plain Greek yogurt 130 23g 1g 7g
1 cup skim milk 80 8g 0g 12g
Calories
20g whey protein isolate 90
1 baked chicken breast 70
1 large boiled egg 80
1 oz unsalted almonds 170
1 cup plain Greek yogurt 130
1 cup skim milk 80
Protein
20g whey protein isolate 20g
1 baked chicken breast 15g
1 large boiled egg 6g
1 oz unsalted almonds 6g
1 cup plain Greek yogurt 23g
1 cup skim milk 8g
Fat
20g whey protein isolate 0g
1 baked chicken breast 1g
1 large boiled egg 5g
1 oz unsalted almonds 15g
1 cup plain Greek yogurt 1g
1 cup skim milk 0g
Sugar (lactose)
20g whey protein isolate 0g
1 baked chicken breast 0g
1 large boiled egg 1g
1 oz unsalted almonds 1g
1 cup plain Greek yogurt 7g
1 cup skim milk 12g
The high protein concentration of whey protein isolate is also helpful for people who struggle to eat enough, such as those with limited appetites.

Amount of food required to provide 20 grams of protein.^

Amount of food required to provide 20 grams of protein.Amount of food required to provide 20 grams of protein.
To preserve muscle mass, protein recommendations during weight loss are up to 2x HIGHER

During weight loss, as much as 33% of weight lost may come from muscle. Muscle mass isn’t just important for athletes and gym-goers – it’s essential for activities of daily living. Studies show increased protein intakes during weight loss preserve muscle mass, leading to more favorable body compositions at the end of the weight loss period. For these reasons, protein recommendations are much higher for people losing weight. 

avg weight loss & avg fat lossAverage weight lossAverage fat-free mass lost
Higher protein weight loss diets lead to similar or greater weight loss while preserving more fat-free mass than standard protein weight loss diets.1

Protein recommendations, such as those from the Academy of Nutrition and Dietetics Nutrition Care Manual or findings from systematic reviews2, can be 50%-100% higher for people losing weight than the standard recommendation of 0.8 g/kg/body weight per day, with older adults, athletes, and those undergoing very-low calorie diets needing the most protein during weight loss.

Condition Protein requirement (% of normal requirement)
Average requirement 100%
Aging 150%
High activity 150%
Weight loss 200%

However, according to the National Health and Nutrition Examination Survey (NHANES), intakes of protein are typically lower than these recommendations. Protein supplementation can be an effective way to bridge the gap for those who have trouble eating enough protein from food.

Avg US protein intakeAverage US protein intake
Protein supplementation can help meet increased protein needs 
spoon

1 Tablespoon of ISOPURE® Zero Carb Unflavored Protein Powder = 5g protein


(Add to oatmeal, dips, scrambled eggs, mashed potatoes)

three bowls of food
half filled measuring cup

Half scoop = 12.5g protein

(Add to yogurt, soups, sauces, casseroles) 

hot bowl of food, bottles and pot
measuring cup

Whole scoop = 25g protein

(add to smoothies, protein shakes, recipes) 

cup, shaker and bowl of vegetables

References:

1Hector et al, Whey Protein Supplementation Preserves Postprandial Myofibrillar Protein Synthesis during Short-Term Energy Restriction in Overweight and Obese Adults, The Journal of Nutrition, Volume 145, Issue 2, 2015, Pages 246-252, ISSN 0022-3166, available at https://www.sciencedirect.com/science/article/pii/S0022316622086163

2Wycherley TP, Moran LJ, Clifton PM, Noakes M, Brinkworth GD. Effects of energy restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2012 Dec;96(6):1281-98. doi: 10.3945/ajcn.112.044321. Epub 2012 Oct 24. PMID: 23097268. Available at https://pubmed.ncbi.nlm.nih.gov/23097268/.

*Heather J Leidy, Peter M Clifton, Arne Astrup, Thomas P Wycherley, Margriet S Westerterp-Plantenga, Natalie D Luscombe-Marsh, Stephen C Woods, Richard D Mattes, The role of protein in weight loss and maintenance, The American Journal of Clinical Nutrition, Volume 101, Issue 6, 2015, Pages 1320S-1329S, ISSN 0002-9165, https://doi. org/10.3945/ajcn.114.084038.

^Modified from Pinckaers, P.J.M., Trommelen, J., Snijders, T. et al. The Anabolic Response to Plant-Based Protein Ingestion. Sports Med 51 (Suppl 1), 59–74 (2021). Available at https://doi.org/10.1007/s40279-021-01540-8

 

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